Family name Manuel Alexis (Manuel Alexis 
) , in all the world, is a rare last name. The surname Manuel Alexis is habitual in Chile, where it is quite a rare surname, and Spain, where it is a rare surname. More frequently, Manuel Alexis is the forename as well as the last name.
| VARIANT | COUNTRY |
|---|---|
| Manuel Alexis | Costa Rica, Peru, Dominican Republic, Spain, Chile |